NexION 2000B ICP Mass Spectrometer

Rice represents a dietary staple for over half of the world's population. However, in recent years, concerns have been raised over the presence of high levels of arsenic (As), where this carcinogenic metalloid can be accumulated at levels far exceeding ambient concentrations. Since China is the worl ...

Cassava is a root vegetable and a major source of calories and carbohydrates in many countries around the globe. As one of the most important staple crops, its levels of harmful chemicals and pathogens are strictly controlled – these include organic chemicals and heavy metals. Metals, such as cadmiu ...

In this work, we demonstrate that PerkinElmer's NexION® 2000 ICP-MS, with its unique RF generator and ion optics, coupled with the Syngistix™ Nano Application Software Module, can be used to accurately measure and characterize NP sizes of 10 nm and smaller, both alone and in a mixture of NPs of vari ...

This application note presents a high throughput method evaluating 27 analytes in drinking water following U.S. EPA 200.8 with a 3-5 fold reduction in sample analysis time through the use of the HTS high throughput sample introduction system fully integrated with the NexION® ICP-MS and Syngistix™ fo ...

This work demonstrates a robust method using SP-ICP-MS technology to detect CeO2 NPs which were extracted from soil samples with tetrasodium pyrophosphate (TSPP). Over the past few decades, engineered nanoparticles (ENPs) have been increasingly used in many commercial products. As a result, more and ...

This work has demonstrated the ability of the NexION 2000 ICP-MS to analyze both natural and drinking water samples in Standard (i.e. non-cell) mode, in accordance with U.S. EPA Method 200.8. Accuracy has been demonstrated through the analysis of several reference materials and spike recoveries, wit ...

Plant-based foods using ingredients derived from fruits, nuts, vegetables, grains, and legumes, have gained increased attention for a variety of reasons, including but not limited to nutritional, environmental, sustainability, and ethical issues. While they have many benefits, they also present chal ...

To better understand the impact of nanoparticles, several key characteristics need to be assessed, such as concentration, composition, particle size, shape and other surface characteristics. The NexION® SP-ICP-MS, with Syngistix™ Nano Application software module, combines fast, accurate data acquisi ...

With the increasing development of high-tech applications, rare earth elements (REEs) are considered key elements for modern and future industries. Globally, there is growing pressure for analytical solutions that can accurately characterize and quantify REE content in a high-throughput manner to me ...

With the development of nanotechnology and the increased use of nanoparticles (NPs) in numerous products and processes, the need to characterize them has also grown. Nanoparticles come in a wide variety of compositions, with silica dioxide (SiO2) nanoparticles being used in many areas. For successfu ...

Measuring the amount of metals in CNTs presents a challenge. High levels can be measured directly in the solid by several techniques, including XRF and TEM, while low-level analysis requires complete digestion of the sample prior to analysis by ICP-OES or ICP-MS.

Through the years, both industry and analytical instrumentation have advanced. With the development of new chemicals and processes, new pollutants may enter the environment. However, the capabilities of analytical instruments have also increased, allowing the measurement of ever lower levels of envi ...

Boron (B) is studied for its isotope ratio composition in a range of paleoproxy, geochemical, nuclear, medical, and archeological applications. ICP-MS is recognized as a powerful technique for boron isotope analysis. Quadrupole ICP-MS is versatile and not exclusively dedicated to isotope ratio measu ...

With the increasing use of nanomaterials in a wide variety of products and processes, the need to measure and characterize them has also grown. Single particle ICP-MS (SP-ICP-MS) was developed specifically for metallic and metal-containing engineered nanoparticles (NPs) and is gaining popularity due ...

With growing concern about the state of the environment, more and more devices are being powered by lithium batteries due to their higher capacities, longer lives, and ability to be recycled, in comparison to conventional batteries. As with all consumer goods, safety and performance are critical and ...

Selenium (Se) is an essential element at trace levels, toxic at higher levels, and exists in several oxidation states in a variety of inorganic and organic compounds. Consequently, the chemistry of selenium is complex in both the environment and biota. For the determination of selenium species in wa ...

Concentrations of toxic elements in foods are present at trace to ultra-trace levels, requiring sensitive and reliable analytical techniques for accurate measurement. ICP-MS is a powerful technique with multi-element detection capabilities, low detection limits, high speed of analysis, and wide line ...

For many children around the globe, commercial baby foods are the main source of nutrients and energy, and therefore their quality and safety are critical and must be monitored. In March 2021, the U.S. House of Representatives introduced the “Baby Food Safety Act of 2021” to regulate the presence of ...

Eye drops are commonly used medications which are available both over-the-counter and as prescriptions in various forms. Because eye drops are classified as a parenteral medication and have relatively large daily doses, the inorganic components in eye drops must be present at low concentrations. As ...

Nickel-based superalloys benefit from high heat resistance, high melting points, retention of mechanical and chemical properties at high temperatures, and high corrosion resistance, among others, and are therefore widely used in challenging environments, such as aircraft and power generation turbine ...

The elemental concentration of fluid inclusions in geological samples provides information about geological processes that lead to the formation of ores and minerals. Laser ablation-ICP-MS (LA-ICP-MS) is the preferred technique for measuring elemental concentrations in fluid inclusions due to its ab ...

Titanium dioxide (TiO2) nanoparticles are commonly used in sunscreens as part of the formulation to block the sun’s harmful UV rays. As the use of nanoparticles (NPs) in consumer products has increased, concern has risen as to the health and environmental effects of nanoparticles. Since sunscreens c ...

Cisplatin, carboplatin, and oxaliplatin are the most widely used of platinum-based cancer chemotherapy drugs in the Western world. Cisplatin's effectiveness is due to its ability to bind to the DNA, resulting in DNA-platinum (Pt) adducts, which bend the DNA. The cells must then repair the DNA damage ...

This work demonstrates the ability of PerkinElmer's NexION 2000 ICP-MS to perform accurate, stable analyses of blood and serum samples, leveraging the benefits of the Universal Cell and the ability to use three cell gases in a single method.

Due to rising concerns over the carcinogenic properties of hexavalent chromium (Cr6+) in drinking water, many national and regional water standards are looking to lower the maximum allowable levels of total chromium and hexavalent chromium in potable waters. And in order to assess trace concentratio ...

Nanoparticles (NPs) have been of significant interest over the last two decades as they offer attractive benefits for drug delivery to overcome limitations in conventional chemotherapy. Nanoparticles can be engineered to carry both drugs and imaging probes to simultaneously detect and treat cancer. ...

Separating and measuring the physical and chemical properties of monometallic and bimetallic engineered nanoparticles (NPs) is challenging, especially when mixtures of NPs consist of particles of similar size, composition, and especially when present at low concentrations. Fully characterizing suspe ...

Testing for harmful metal(loid)s that may be included in raw materials, processes, paints and additives used in the manufacturing processes of children's toys has been mandated by the regulation EN 71-3. This regulation recommends specific testing methods and maximum allowable concentrations of leac ...

The United States Pharmacopeia (USP) has announced that its new standards for elemental impurities in drug products has been implemented since January 1, 2018. General Chapters <232> and <2232> specify the list of elements and their permissible daily exposure (PDE) limits based on the route of admin ...

This work investigated the transfer of Ag and CuO nanoparticles from consumer products via simulated dermal contact by using textile wipes as a surrogate using PerkinElmer’s NexION® ICP-MS single particle analyzer with the unique Syngistix™ Nano Application software module for data collection and an ...

Quality and consistency of medicines is critical to ensuring their identity, strength, and purity is at a safe level for human consumption. That's why we rely on strict guidelines – to guarantee medications that make it to the shelves are exactly what they claim to be. This guide helps provide a sim ...

Feed milling today is a complex business, and agribusinesses both large and small need to balance the nutritional and safety needs of livestock with availability of raw ingredients and their seasonality and variability. Add to that the valuable supplementation and medication that millers supply, and ...

It’s clear, glass has a variety of uses, from practical to technological to decorative. In particular, float glass is widely used in architecture, automotive, transportation, photovoltaic, and solar industries. For glass testing labs around the world, we offer highly accurate and tailored solutions ...

The grain industry is very complex. It’s global, diverse, and can also present analytical challenges. Today’s grain users demand more when it comes to quality, safety, and uniformity. In addition, they seek diverse products with unique characteristics. PerkinElmer is equipped to help the grain indus ...

Food testing labs like yours are constantly challenged with accurately analyzing samples quickly and efficiently - all while striving to reduce costs due to market forces. Your commitment to ensuring meat and seafood are safe for consumption, as demand increases, is an uphill battle. Our commitment ...

Unrivaled ppq detection limits. Unparalleled usability. Finally analysts can have the best of both worlds with the NexION® 2000 ICP-MS, featuring an array of unique technologies that combine to deliver the highest performance no matter what your analytical challenge. Discover the effortless versatil ...

Oil refineries and natural gas producers around the world require their lab operations to perform large numbers of analyses before their products are used in industries and by consumers. Detection of even the slightest impurities, accurate process control and hydrocarbon distribution analysis is cri ...

The International Conference on Harmonization Guideline for Elemental Impurities Q3D (ICH Q3D) has established maximum permitted daily exposure limits for elemental impurities in pharmaceutical products. In combination with the U.S. Pharmacopeia’s (USP) Chapters <232> and <233> on elemental impuriti ...

Download your complete PDF catalog containing all the consumables needed to keep your Atomic Absorption, ICP-OES, and ICP-MS instruments up and running.

Built on robust, flexible technology that enables labs to comply with ISO 17294-2, PerkinElmer’s ISO 17294 Water Analyzer allows you to quickly begin analyzing drinking and surface water samples using a complete, end-to-end workflow, including instrumentation, software, consumables, validated method ...

The S20 series is the next generation of high-performance, robust, and agile autosamplers designed specifically for PerkinElmer’s spectroscopy platforms - atomic and molecular. The series is comprised of two autosamplers: the S23 with three racks and the S25 with five racks. They are designed to mee ...

Today’s sustainable solutions are opening exciting new ways for businesses to fuel economic growth, while minimizing adverse impact on people and the planet. Laboratories are also working sustainability into their business plans to reduce downtime, waste, and costs – and in many cases, improve their ...

Atomic spectroscopy is a family of techniques for determining the elemental composition of an analyte by its electromagnetic or mass spectrum. Several analytical techniques are available: Atomic absorption (AA): flame and graphite furnace Inductively coupled plasma optical emission spectroscopy (ICP ...

Our High Throughput System (HTS) is a uniquely designed modular sample introduction that integrates with the NexION® series of ICP-MS and the Avio® series of ICP-OES to dramatically reduce sample-to-sample time, thereby improving sample throughput while maintaining operation simplicity. The HTS maxi ...

PerkinElmer’s Syngistix Enhanced Security software for AA, ICP and ICP-MS meets the special needs of highly regulated labs such as those that must comply with the U.S. FDA’s 21 CFR Part 11 regulations.

Product Certificate for the NexION 1000/2000

Laser ablation-ICP-MS (LA-ICP-MS) has become an increasingly popular tool for imaging due to its ability to provide spatially resolved elemental information at low concentrations. Many aspects need to be considered when setting up an LA-ICP-MS system for imaging. Laser scanning speed, stage accuracy ...

Unlike other ICP-MS systems on the market that utilize conventional 40-MHz or 27-MHz commercially available generators which are typically customized and modified to work with ICP-MS instruments, the NexION® 1000/2200/5000 ICP-MS systems feature a 34-MHz frequency free-running RF generator, which wa ...

PerkinElmer’s All Matrix Solution (AMS) system provides a number of benefits to simplify analysis of high-matrix samples with the NexION family of ICP-MS instruments. It allows online gas dilution, improving efficiency and preventing contamination, delivering up to 200x dilution and the ability to s ...

Discover how the PerkinElmer Asperon Spray Chamber can deliver "intact individual cells" to ICP-MS Plasma.

Carbon is difficult to measure with ICP-MS because of its high ionization potential and its presence in both the argon used to generate the plasma (primarily in the form of CO2, as an impurity) and in reagents, including acids and water. As a result, extremely high backgrounds exist at both of the n ...

Extractables and leachables studies are critical for maintaining the quality of your drug product and complying with GMP regulations during drug development and final batch release. Exposure to extractables and leachables could have a detrimental impact on the safety and efficacy of a final drug pro ...

With the onset of the COVID-19 pandemic, the use of face masks by the general public has become a critical personal protective measure to minimize person-to-person transmission. While health care workers use medical or surgical masks, the general population uses non-medical, otherwise known as hygie ...

The potential of all solid-state battery (ASSB) technology to revolutionize the battery industry is resulting in new battery designs and material configuration solutions. These advancements will unlock chemistry limitations from traditional battery technologies and enable ASSBs to break through the ...