PerkinElmer’s All Matrix Solution (AMS) system provides a number of benefits to simplify analysis of high-matrix samples with the NexION family of ICP-MS instruments. It allows online gas dilution, improving efficiency and preventing contamination, delivering up to 200x dilution and the ability to support samples with up to 35% total dissolved solids. By introducing a flow of argon into the spray chamber neck, the aerosol stream is diluted, allowing for more efficient ionization, fewer matrix effects, and less deposition on the interface cones, which results in simplified sample preparation and higher quality data.