There are many characteristics to consider when choosing a detector, therefore several detectors have been developed over time to address particular challenges. It is important to consider the chemical nature of the analytes of interest and any potential interferences, when choosing a detector. Additionally, the combined use of complementary or orthogonal detectors is gaining popularity in drug discovery and other screening applications, where complementary information can be generated by separate detectors.
With reference to applications using PerkinElmer LC 300™ HPLC and UHPLC System, this guide will highlight the different detectors available and provide tips to help you choose the most appropriate detector for your liquid chromatography application.