Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to accumulate throughout environmental ecosystems. More recent research has revealed the toxic effects PFASs can have on humans and wildlife and is driving enhanced global regulations and monitoring of their presence in Air, Water and Soil as well as other matrices. With the EPA's recent concentration on PFAS in drinking water, this eBook takes a closer look at the challenges PFAS pose to such analysis. Dive into three topics from subject experts: Overcoming the Challenges of Reducing Background Interference for LC/MS/MS Trace PFAS Analysis, Detecting Environmental PFAS Using Liquid Chromatography-Tandem Mass Spectrometry and the EPA Method 537.1 Application Note.