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The NexSAR™ HPLC, is a next-generation Speciation Analysis Ready system engineered with a completely inert and metal-free fluid path, enabling laboratories to meet low chromatographic background requirements on the most challenging speciation applications. Plus, it is fully customizable, with the flexibility to select only the parts that you need for your application(s).
This system is part of the NexSAR HPLC-ICP-MS Speciation Solution, which couples the NexSAR HPLC with our revolutionary NexION® ICP-MS and is seamlessly integrated using the proven Clarity™ software.
Clarity™ chromatography software (version 8.1 or higher) is part of PerkinElmer’s NexSAR™ HPLC-ICP-MS Speciation Analysis Ready Solution, which couples the NexSAR HPLC to the NexION® ICP-MS in a seamless and integrated platform.
It allows streamlined workflows, from method development through to reporting. Data processing, integration and calibration are straightforward, and for the most discerning users, advanced integration features are also available. Reporting is simple, allowing you to export the data in a number of different formats and personalize your reporting style to suit your individual needs.
Silica based support for larger anionic compounds.
Recommended for the separation of large biomolecules, such as peptides and proteins.
Alternative selectivity to alkyl bonded phases, recommended for aromatic groups. Compatible with highly aqueous mobile phases to facilitate the retention and separation of polar compounds.
Recommended for the separation of large biomolecules, such as peptides and proteins.
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Coumarin (1,2-benzopyrone) occurs as a natural component in some plants, and is utilized as a flavoring ingredient in some foods, tobaccos and cosmetic products. In recent years, coumarin has been added to electronic cigarette liquid nicotine solutions as a flavoring component, producing a complex f ...
Selenium (Se) is an essential element at trace levels, toxic at higher levels, and exists in several oxidation states in a variety of inorganic and organic compounds. Consequently, the chemistry of selenium is complex in both the environment and biota. For the determination of selenium species in wa ...
For reverse phase high performance liquid chromatography (RP HPLC) separations, C18s are the "workhorse" LC columns. They have broad applicability in many industries, but they are not optimized for all application-specific needs, especially for critical separations of similar aromatic compounds. Tha ...
Urine is the matrix of choice as it can be collected easily and in large volumes. The variations within the urine matrix can adversely impact chromatographic separation and LC-MS/MS signal. The present study demonstrates that a simple “dilute and shoot” method coupled with the high sensitivity QSigh ...
Aflatoxins are toxic metabolites produced by two fungi species, Aspergillus flavus and Aspergillus parasiticus, and can be found on various staple foodstuffs around the world. They exist in four major forms and these compounds are both carcinogenic and mutagenic, with B1 being the most potent. Conta ...
In this New Food article we discuss how to get around the challenges of the ever growing cannabis and CBD testing space. Read about our solutions for automated pesticide testing to cannabinoids to regulatory compliance.
Acrylate polymers are utilized for a host of applications due to their varied physical properties and ease of synthesis. These acrylates are sought after specifically for coatings, adhesives, sealants and elastomers (CASE) applications because of their stability, high heat resistance, excellent weat ...
Urea is a white, crystalline solid containing 46% nitrogen. Due to its high nitrogen content, urea is the most widely used source of nitrogen for nitrogen-based fertilizers worldwide. The accurate determination of urea in urea-based fertilizers is important for regulatory and product quality purpose ...
Counterfeiting of pharmaceuticals and the proliferation of substandard drugs constitute a serious health risk for the world population, including both industrialized and developing countries. It is estimated that five to eight percent of the world’s total pharmaceutical sales are counterfeit or of d ...
Sugars are the most important component of soft drinks, candies, and sweets. Therefore, sugars quantitation in syrups used for manufacturing or ready products is of extreme importance. In the USA, not only traditional saccharose is in use, but high fructose corn syrup, the mix of fructose and glucos ...
For more than 40 years, the United States Environmental Protection Agency (EPA) has monitored semivolatile organic compounds (SVOC) in wastes, soils/sediments, and groundwater via its Method 8270. This method is extensive in scope, targeting chemicals found in petroleum/soot (e.g., polycyclic aromat ...
Alkylphenol ethoxylates (APEOs) are common surfactants used in in industrial and consumer detergents and cleaners, as well plastics and many industrial applications. Nonylphenol ethoxylates (NPEOs) belong to the group of non-ionic surfactants and are of particular interest, as they tend to degrade t ...
Knowing the concentration of hexavalent chromium in environmental systems and samples which will be consumed is more important than knowing the total chromium concentration. This is especially true for drinking water. This work describes the use of LC-ICP-MS to measure both trivalent and hexavalent ...
This application note demonstrates a method for the routine sample preparation and quantitative determination of lactose in mozzarella and ricotta cheeses and milk. As the monosaccharaides glucose and galactose can be hydrolytically or enzymatically produced from lactose, these two sugars were also ...
Combination of Immunoaffinity Column with high performance liquid chromatography (HPLC) or LC-MS/MS is a quantitative method for the detection of mycotoxins in samples such as grains, nuts, feed, dairy and more. Samples are purified by the column and then analyzed with HPLC or LC-MSMS.
Meloxicam is a common pharmaceutical drug used to treat pain resulting from various musculoskeletal conditions such as osteoarthritis. It belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs) which are effective in relieving pain and reducing inflammation, although they ...
Measurement of metanephrines and normetanephrine in plasma is challenging due to the low physiological concentrations, their hydrophilic nature1, and time consuming traditional sample preparation. With use of the PerkinElmer QSight® 220 triple quadrupole mass spectrometer, LC-MS/MS analysis was perf ...
Aniline and aniline derivatives are widely used as raw materials and intermediates in the polymer, rubber, dye, pesticide and pharmaceutical industries. Unintended releases of aniliane or its derivatives into the environment pose a serious threat, with release possible during any stage of production ...
In this application, we describe a technique for the monitoring of six cannabinoids, including THC and CBD, in hemp seed oil by HPLC with PDA detection. Figure 1 shows the chemical structures for the six cannabinoids. In recent years, scientific knowledge regarding the composition and health benefit ...
Today, Warfarin is the most widely used anticoagulant in the world, used to thin the blood and prevent clots.1 It was discovered by chance when in the 1920’s cattle in the US were found to be bleeding to death having eaten mouldy hay from sweet clover crops.2 However, the exact identity of the subst ...
Plastic bags are widely used in food packaging due to cost and flexibility, for example breakfast items such as hot steamed buns, oil cake and soybean milk are typically packaged in plastic. Leftovers, supermarket cooked food and even beer, are also packaged with plastic bags. Plastic packaging is v ...
This application outlines the HPLC analysis of honeysuckle granules following the Chinese National Medicine and Pharmacy agency's (NMPA) published TCM formulated granule guidelines. Successfully meet method requirements with the LC 300 instrument and a Chromegabond C18 WR column.
Volatile organic compounds (VOCs) are compounds that can evaporate at ambient temperatures. They are emitted from certain solids or liquids and are prevalent in the environment. VOCs are present in homes and workplaces, originating from many sources, including household and industrial products, offi ...
Organotin compounds are widely used across industry and agriculture, resulting in widespread pollution of various environmental media, including potable water. Among these compounds are tributyltin (TBT), triphenyltin (TPT), dibutyltin (DBT), and diphenyltin (DPT), in the following order of persiste ...
Although apple juice is a healthy, and often preferred, alternative to artificially flavored and carbonated drinks for many parents to give to children, concern has been raised over the presence of arsenic within. This work demonstrates a reversed-phase ion-pairing method for the complete separation ...