QSight LC/MS/MS System

Mycotoxins are toxic secondary metabolites produced by various fungal species growing in foods and animal feeds. To minimize risk and protect consumers, mycotoxin levels in foods and/or feeds have been regulated by agencies in many countries around the world. A number of analytical methods for the d ...

Testing for the levels of pesticide and mycotoxins in cannabis is important to ensure consumer safety and quality control. In this work, the PerkinElmer application development team analyzed all 66 pesticides (including very hydrophobic and chlorinated pesticides typically analyzed by GC-MS/MS) and ...

Acrylamide is a probable carcinogen organic compound that is found in some foods that are cooked at elevated temperatures. It’s origins are due to the condensation of the amino acid asparagine and glucose as part of Maillard reaction. In 2002, Acrylamide was found to be present in french fries and b ...

Aflatoxin B1 is considered to be the most genotoxic of the mycotoxins, and, when ingested by cows, is converted to aflatoxin M1 which has been shown to cause liver cancer in certain animals.

Several directives throughout the EU provide guidance on environmental quality standards for water, and define more than 30 priority substances as significant risk to humans. Many of the monitoring limits within these directives are set at low µg/L (ppb) levels, and as such, require highly sensitive ...

Due to the large number of pesticides potentially used in rice production, the use of multi-residue methods capable of determining many pesticides in one single run is the most efficient approach. In this study, a fast, sensitive and selective multiresidue method has been developed for analysis of o ...

Mycotoxins produced by fungi as toxic secondary metabolites, leave grains, maize and cereals particularly vulnerable. With this in mind, and considering that an estimated 25% of all crops show some signs of mycotoxin contamination, many countries have established regulatory guidelines for maximum my ...

Per- and polyfluoroalkyl substances (PFAS) are man-made carbon-chain based compounds that have been widely used in commercial and industrial products such as fire-fighting foams, water proofing treatments for clothing and furniture, nonstick cookware, and paper. PFAS’ are thermally and chemically st ...

This application note details an online-SPE-LC/MS/MS method for the determination of polycyclic aromatic hydrocarbons (PAHs) in drinking water samples which reaches the low detection levels required by EU regulations. The method couples the SP50 UHPLC system to the QSight® 400 series triple-quad mas ...

Analysis of target pesticide residues in berries using a unique laminar flow UHPLC-ESI-MS/MS

The increasing demand for organic products, evolving global regulations, and improving accessibility of agricultural hubs to global markets results in pressure on food safety precautions. Translating, in part, to increased pesticide residue analysis demand. Mass spectrometry meets pesticide analysis ...

Aflatoxin B1 is often found in animal feeds such as corn, cottonseed cake, groundnut meal, and other agricultural commodities. When these contaminated feeds are ingested by milk-producing animals, such as cattle, aflatoxin B1 can be converted to aflatoxin M1 (a hydroxy derivate of aflatoxin B1) by o ...

In this study we show two methods for the analysis of over 30 antibiotics and veterinary drugs in milk regulated by the Food Safety and Standards Authority of India (FSSAI). For polar analyte analysis, such as aminoglycoside antibiotics (apramycin, spectinomycin, and neomycin) in milk, a mixed mode ...

Polycyclic aromatic hydrocarbons (PAHs) can contaminate foods during smoking, heating, and drying processes that allow combustion products to come into direct contact with food. They can also enter food supply chains through contaminated air and water, and accumulate in various food chains. Regulati ...

Glyphosate is a very polar compound with high solubility in water and low solubility in most organic solvents and, as such, requires methods based on derivatization which are labor-intensive and time consuming. The present work shows a 12 minute LC-MS/MS method with an amino-based column to analyze ...

Agricultural growing of hemp products for the purposes of cannabidiol (CBD) extraction was legalized in the United States with the passing of the Agricultural Improvement Act of 2018. Since the act passed, heightened concern over the use of pesticides in hemp production has been appreciated. However ...

Quantitative analysis of cell culture media components is a critical step in upstream bioprocess development. A comprehensive and quantitative understanding of cellular metabolic components could lead to a greater understanding of the process impacts on cell growth, productivity, and product quality ...

Estrogen plays an important role in the human body, but excess concentrations of endogenous estrogens, a known endocrine disrupting compound (EDC), in urine have been linked to the development and growth of breast cancer and tumors in females. Endogenous estrogens, including estrone (E1), 17ß-estrad ...

This application note outlines a new workflow with one instrument platform (LC/MS/MS) method that is ideal for simultaneous analysis of pesticide and mycotoxins residue in cannabis. This application note demonstrates the performance of a LC/MS/MS ESI and APCI method with a single solvent extraction ...

Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals developed in the 1940s, and widely used for their surfactant properties. Due to their prevalent use within consumer products and persistence in nature, PFAS have leached into the air, soil, and water, making exposure wides ...

Tobacco specific nitrosamines (TSNA) are a group of chemicals found in tobacco, smokeless tobacco, and tobacco smoke. They are widely considered to be among the most important arcinogens in tobacco products and cigarette smoke. Tobacco product manufacturers must report their contents in tobacco prod ...

Simultaneous detect and quantify cortisol and cortisone in urine using the QSight 200 series mass spectrometer coupled with a commercially available kit.

Discover a fast and reliable UHPLC-MS/MS method for the determination of HVA, VMA, and 5-HIAA acid in urine using the QSight 200 series mass spectrometer and a commercially available kit.

EU water policies are reevaluated on a consistent basis to ensure water sources do not contain contaminants at levels above regulatory levels. As regulations are reviewed, regulatory limits are often lowered, and analytical techniques must adapt to meet the new stringent requirements. In this applic ...

The use of cannabis concentrates and CBD products (edibles, topicals, vape products, etc.) has increased in popularity as new regulation has been passed legalizing medicinal and recreational use in a number of states and provinces. Testing to ensure that pesticide and mycotoxin levels in cannabis pr ...

The Grape crop is one of the most important fruit crops consumed in the world. Grapes are consumed both as fresh and as processed products, such as wine, jam, juice, jelly, grape seed extract, raisins, vinegar and grape seed oil. A large variety of pesticides are used in grape production throughout ...

Today’s plastics are some of the most used materials on a global volume basis. Broadly integrated into today’s industrial and commercial lifestyles, they make a major, irreplaceable contribution to virtually every product category. In this compendium you will find a wide range of applications for po ...

This application note describes a novel LC/MS/MS method with dual ESI and APCI source for analysis of different pesticides and mycotoxins residues regulated by seven different states in cannabis samples as of June 2021. The straightforward sample preparation procedure allows to achieve short sample ...

Haloacetic acids (HAAs) are a class of undesired by-products resulting from the reaction of chlorinated disinfectants with natural organic matter in water, Which is known to be carcinogenic. The Japan Ministry of Health revised the inspection method for HAAs, which led to expansion of the analytical ...

Per- and polyfluoroalkyl substances (PFAS) are a diverse group of synthetic organic compounds which have been utilized as aqueous film forming foams (AFFF) for firefighting purposes, and as stain and water resistant coatings on a number of consumer products such as clothing, furniture or cookware. P ...

A simple and sensitive method for the simultaneous determination of plant growth regulators

Pesticides can adversely affect human health through the food we consume but can also leach into soil and groundwater and impact us through the environment. To keep up with a complex and constantly changing regulatory environment, your pesticide analysis solution needs to keep up with your burgeonin ...

Over the past decade, awareness and concern about Per- and Polyfluoroalkyl Substances (PFAS) has grown and led to more in-depth analysis of these compounds and the effects that they can have on human health. Due to their inert nature, PFASs are persistent organic pollutants and have been found to ac ...

Demand for cannabis testing services continues to climb as more US states and countries around the globe implement regulated adult-use markets. The cannabis testing sector in the US, like many facets of the cannabis industry, is challenged by the complexity of working with a federally illegal but st ...

This poster lays out our whole material characterization range for the analysis of polymers and plastics. Find ideal techniques and instruments at each stage in the polymer manufacturing process: Resin Development - Resin Manufacture - Compound Development - Compound Manufacture - Product Forming - ...

Our modular Simplicity 3Q™ software is ideal for acquiring, quantifying and reporting

Ion Transmission Through a Quadrupole Ion Guide Under the Combined Influence of Viscous Flow and RF

Theoretical Studies of Swirling Flow and Heating Methods on Droplet Evaporation in a Heated Coaxial

Analytical laboratories face many challenges when analyzing contaminants such as Pesticides, PFAS, mycotoxins in complex matrices. These samples often require time-consuming sample prep and regular maintenance of the analytical technology.

Due to PFAS persistence in the environment and potential health risks, regulations have been undergoing constant change and refinement.

With our extended portfolio of cannabis testing products featuring best-in-class sample homogenization platforms, ICP-MS, LC/MS-MS, Headspace-GCMS, UHPLC and FTIR instruments and consumables, we help drive analytical best practices and operating procedur

PFAS matrix-induced contamination poses various challenges for analytical laboratories, from the risk of achieving low detection limits and lab downtime.

PFAS compounds are ubiquitous throughout the environment and accumulate everywhere, including in the lab.

As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.

Stricter regulations demanding lower detection limits, increased throughput and efficiency demand that labs need an LC/MS/MS solutions that offers robust and reliable performance while ensuring efficiencies.

When examining complex compounds like PFAS, pesticides, and mycotoxins using LC/MS/MS in challenging matrices, laboratories encounter issues such as system contamination, matrix effects, and the laborious task of source cleaning.

The PerkinElmer QSight LC/MS/MS is used for many applications, including forensic toxicology.

In this presentation, prepare to learn all of the best practices for Liquid Chromatography Mass Spectrometry from consumables all the way to instrumentation and analysis. This talk is well-suited for all LC/MS applications including environmental testing

In this latest webinar, LC–MS/MS PerkinElmer expert Dr. Avinash Dalmia describes how LC–MS/MS based systems and methods can overcome the challenges associated with the analysis of pesticides and mycotoxins regulated by Colorado state in hemp with dual ES

Growing environmental concern has led to stricter regulations of drinking water and water supplies over the past decade including routine monitoring and detection of cyanotoxins resulting from ever-growing algae blooms. This talk discusses the utiliza

PerkinElmer offers a portfolio of high-performance solutions to optimize your laboratory workflow for PFAS analysis.

Pharmaceutical and personal care products (PPCPS) are an emerging environmental concern and include human and veterinary prescriptions, over-the-counter medications, sunscreens, lotions, soaps and insect repellents. In this webinar we demonstrate the a

In this podcast, we meet with Simone Rumph, a first generation college student, to discuss her research on post-mortem drug identification.

In this short webinar, PerkinElmer’s Environmental Leader, Tom Hey, discusses simplified PFAS method implementation with the comprehensive PerkinElmer LC/MS/MS workflow, featuring ready-to use consumables kits, reagents and software-driven compliance.

Emerging contaminants, including perfluoroalkyl surfactants (PFAS) and Pharmaceuticals and Personal Care Products (PPCPs), have garnered increasing interest in recent years as their bioaccumulative nature and endocrine disrupting potential have become..

When it comes to analyzing environmental or food samples, including water, soil, cannabis or any solid matrices, labs need to meet stricter regulations that demand lower detection limits.

The US EAP Method 537.1 is used for the determination of selected PFASs in drinking water by solid phase extraction and liquid chromatography/tandem mass spectrometry. This talk discusses the utilization of the PerkinElmer QSight® Triple Quadrupole LC